Recent Publications

Gupta, B., Saxena, A., Perillo, M. L., Wade-Kleyn, L. C., Thompson, C. H., & Purcell, E. K. 2024. Structural, Functional, and Genetic Changes Surrounding Electrodes Implanted in the Brain. Accounts of Chemical Research, 429-439.

Gregory B, Thompson CH, Salatino JW, Railing M, Gupta B, Williams K, Beatty J, Cox CL, Purcell EK. 2023. “Structural and Functional Changes of Pyramidal Neurons in Primary Motor Cortex at the Site of an Implanted Microelectrode Array.” Acta Biomaterialia, 168, 429-439.

Gupta B, Perillo ML, Siegenthaler JR, Christensen IE, Welch MP, Rechenberg R, … Li W, Purcell EK. 2023. In Vitro Biofouling Performance of Boron-Doped Diamond Microelectrodes for Serotonin Detection Using Fast-Scan Cyclic Voltammetry. Biosensors, 13(6), 576.

Thompson CH, Evans B, Zhao D, Purcell EK. 2023. “Spatiotemporal Expression of RNA-Seq Identified Proteins at the Electrode Interface.” Acta Biomaterialia. 164, 209-222.

Riggins TE, Whitsitt Q, Hunter E, Hunt B, Thompson CH, Purcell EK. 2023. “Gene Expression Changes in Cultured Reactive Rat Astrocyte Models and Comparison to Device-Associated Effects in the Brain.” bioRxiv.

Gupta B, Perillo ML, Christensen IE, Siegenthaler JR, Rechenberg R, Becker MF, Li W, Purcell EK. 2023. “Waveform Development for Neurotransmitter Detection on Novel Boron-Doped Diamond Microelectrodes.” In 11th International IEEE EMBS Conference on Neural Engineering (NER).

    Whitsitt Q, Koo B, Celik M, Evans B, Weiland JD, Purcell EK. 2022. “Spatial transcriptomics as a novel approach to redefine electrical stimulation safety.” In press, Frontiers in Neuroscience (special issue).

    Riggins TE, Li W, Purcell EK. 2022. “Atomic Force Microscope Characterization of the Bending Stiffness and Surface Topography of Silicon and Polymeric Electrodes.” In 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’22).

    Moore MG, Thompson CH, Reimers MA, Purcell EK. 2022. “Differential Co-Expression Analysis of RNA-Seq Data Reveals Novel Potential Biomarkers of Device-Tissue Interaction.” In 44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’22).

    Quentin Whitsitt, Bella Patel, Brad Hunt, Erin K. Purcell. “A Spatial Transcriptomics Study of the Brain-Electrode Interface in Rat Motor Cortex.” Biorxiv 2021. ​​

    Della Valle, Elena, Beomseo Koo, Paras R. Patel, Quentin Whitsitt, Erin K. Purcell, Cynthia A. Chestek, and James D. Weiland. “Electrodeposited platinum iridium enables microstimulation with carbon fiber electrodes.” Frontiers in Nanotechnology: 91. 2021.

    Cort H. Thompson, Akash Saxena, Nicholas Heelan, Joseph W. Salatino, Erin K. Purcell. “Spatiotemporal Patterns of Gene Expression Surrounding Implanted Silicon Electrode Arrays.” Journal of Neural Engineering. 2021. 

    Erin K. Purcell, Michael F. Becker, Yue Guo, Seth A. Hara, Kip A. Ludwig, Collin J. McKinney, Elizabeth M. Monroe et al. “Next-Generation Diamond Electrodes for Neurochemical Sensing: Challenges and Opportunities.” Micromachines 12, no. 2 (2021): 128.

    Fan, B., Rusinek, C.A., Thompson, C.H., Setien, M., Guo, Y., Rechenberg, R., Gong, Y., Weber, A.J., Becker, M.F., Purcell, E. and Li, W., 2020. “Flexible, diamond-based microelectrodes fabricated using the diamond growth side for neural sensing.” Microsystems & Nanoengineering. 2020. 6(1), pp.1-12.​​

    Monica Setien, Kylie R. Smith, Kaleb Howard, Kathleen Williams, Steve T. Suhr, and Erin K. Purcell. “Differentiation and characterization of neurons derived from rat iPSCs.” Journal of Neuroscience Methods. 2020. 108693.​

    Cort Thompson, Ti’Air Riggins, Paras R. Patel, Cynthia A. Chestek, Wen Li, and Erin K. Purcell. “Toward guiding principles for the design of biologically-integrated electrodes for the central nervous system.” Journal of Neural Engineering, 17(2), 021001, 2020. 

    Takashi DY Kozai and Erin K. Purcell, “Pipette-integrated microelectrodes.” Nature Biomedical Engineering, Volume 3, Issue 9, pp. 682-683, 2019.

    Laura Cabrera, Charles Sadle, and Erin Purcell, “Neuroethical considerations of high-density electrode arrays.” Nature Biomedical Engineering, In press, 2019.

    Heyu Yin, Ehsan Ashoori, Sina Parsnejad, Joseph W. Salatino, Erin K. Purcell, and Andrew J. Mason, “Microfabricated Capacitive Electrodes for High Channel Count ECoG Recording.” In 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER), pp. 839-842. IEEE, 2019.

    Joseph W. Salatino, Arya P. Kale, and Erin K. Purcell. “Alterations in ion channel expression surrounding implanted microelectrode arrays in the brain.” bioRxiv (2019): 518811.

    Nicholas J Michelson, Alberto L Vazquez, James R Eles, Erin K Purcell, Joseph W Salatino, ​​Jordan J Williams, X Tracy Cui, and Takashi DY Kozai, “Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface” Journal of neural engineering, Volume 15 Issue 3, 2018.

    Haitao Li, Sina Parsnejad, Ehsan Ashoori, Erin K Purcell,  Cort Thompson, and Andrew J Mason “Ultracompact microwatt CMOS current readout with picoampere noise and kilohertz bandwidth for biosensor arrays” IEEE transactions on biomedical circuits and systems, Volume 12, Issue 1, pp. 35-46, 2018.

    Cory A Rusinek, Yue Guo, Robert Rechenberg, Michael F Becker, Erin Purcell, Matthew Verber, Collin McKinney, Wen Li, “All-Diamond Microfiber Electrodes for Neurochemical Analysis”, Journal of The Electrochemical Society, Volume 165, Issue 12, pp. G3087-G3092, 2018.

    Bailey Winter, Sam Daniels., Joseph W Salatino, & Erin K Purcell (2018). “Genetic Modulation at the Neural Microelectrode Interface: Methods and Applications.” Micromachines, 9(10), 476.

    Wasif Khan, Monica Setien, Erin Purcell and Wen Li, “Micro-reflector Integrated Multichannel µLED Optogenetic Neurostimulator with Enhanced Intensity”, Front. Mech. Eng. | doi: 10.3389/fmech.2018.00017

    Ehsan Ashoori, Heyu Yin, Sina Parsnejad, Joseph Salatino, Erin Purcell, and Andrew Mason, “ECoG Electrode Array with Embedded Coupling Capacitors for Area Efficient Neural Recording.” In 2018 IEEE Biomedical Circuits and Systems Conference (BioCAS) (1-4).